Fig. 1

Temporal Evolution of HIV RNA Levels and Antiretroviral Treatment History This figure illustrates the patient's HIV RNA levels (copies/mL) over time (2007–2023) on a logarithmic scale. Resistance test results during virologic failure (VF) and viral rebound events are indicated in yellow boxes, showing key mutations in NRTI, NNRTI, PI, and INSTI classes. Sequential antiretroviral regimens are shown at the bottom, with significant changes marked by transition points. The initial diagnosis data (Feb 2007) is highlighted in blue, showing baseline HIV RNA and CD4+ T cell counts