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Table 5 Viral loads comparison of HPV33 E6/E7 variant/mutation

From: Study on the detection rate, genetic polymorphism, viral load, persistent infection capacity, and pathogenicity of human papillomavirus type 33

Variant/mutation

with

without

p

t

E6 prototype

4.62 ± 0.90

4.65 ± 1.02

0.786

0.27

A213C (K35N)

4.55 ± 1.01

4.65 ± 0.91

0.494

0.69

A364C (N86H)

4.59 ± 1.07

4.63 ± 0.91

0.790

0.27

A387C (K93N)

4.52 ± 1.05

4.65 ± 0.90

0.380

0.88

A446G (Q113R)

4.51 ± 1.10

4.65 ± 0.90

0.388

0.87

G542A (R145K)

5.72 ± 0.84

4.60 ± 0.92

0.003

2.96

E7 prototype

4.64 ± 0.90

4.57 ± 1.03

0.611

0.51

C706A (A45E)

4.58 ± 0.90

4.63 ± 0.93

0.859

0.18

C706T (A45V)

4.61 ± 0.89

4.63 ± 0.93

0.950

0.60

A862T (Q97L)

4.47 ± 1.09

4.65 ± 0.90

0.265

1.12

E6 + E7 prototype

4.60 ± 0.90

4.68 ± 0.99

0.543

0.61

  1. Note The data with significant differences are in bold. “With” means carrying/belonging to the variant/mutation, while “Without” means not carrying/not belonging to the variant/mutation. The numbers below “With/Without” represent the mean logarithmic value of viral load (units: log10 copies per 10,000 cells)
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Virology Journal

ISSN: 1743-422X