Table 2 Risk analysis of death by EBV DNA load and infection status
Groups | N | Survival, n (%) | Death n (%) | Crude | Adjusted a | |||
|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | |||||
Infection Status | ||||||||
No-infection | 8,269 | 8,230 (99.53) | 39 (0.47) | 0.76 (0.32–1.80) | 0.534 | 0.67 (0.28–1.58) | 0.357 | |
Past-infection | 6,722 | 6,605 (98.26) | 117 (1.74) | 2.84 (1.25–6.48) | 0.013 | 2.89 (1.27–6.59) | 0.011 | |
Primary Infection | 969 | 963 (99.38) | 6 (0.62) | 1 (Reference) | 1 (Reference) | |||
Unknown | 17,449 | 17,354 (99.46) | 95 (0.54) | 0.88 (0.38–2.01) | 0.759 | 0.95 (0.42–2.18) | 0.909 | |
Activation-IgG+ | 2,547 | 2,510 (98.55) | 37 (1.45) | 2.37 (0.99–5.62) | 0.051 | 2.48 (1.04–5.89) | 0.040 | |
EBV DNA copies/mL | ||||||||
< 400 | 32,483 | 32,227 (99.21) | 256 (0.79) | 2.63 (0.65–10.58) | 0.175 | 2.47 (0.61–9.94) | 0.204 | |
400-1 × 103 | 663 | 661 (99.7) | 2 (0.3) | 1 (Reference) | 1 (Reference) | |||
1 × 103-1 × 104 | 1,393 | 1,385 (99.43) | 8 (0.57) | 1.91 (0.40–9.02) | 0.414 | 1.88 (0.40–8.88) | 0.426 | |
1 × 104-1 × 105 | 764 | 758 (99.21) | 6 (0.79) | 2.62 (0.53–13.01) | 0.240 | 2.47 (0.50-12.27) | 0.270 | |
1 × 105-1 × 106 | 434 | 420 (96.77) | 14 (3.23) | 11.02 (2.49–48.72) | 0.002 | 10.53 (2.38–46.59) | 0.002 | |
> 1 × 106 | 219 | 211 (96.35) | 8 (3.65) | 12.53 (2.64–59.47) | 0.001 | 11.98 (2.52–56.87) | 0.002 | |