Table 1 General characteristics of the population, N (%)
Variables | N 35,956 | EBV DNA copies/mL, n (%) | P | |||||
|---|---|---|---|---|---|---|---|---|
< 400 | 400-1 × 103 | 1 × 103-1 × 104 | 1 × 104-1 × 105 | 1 × 105-1 × 106 | > 1 × 106 | |||
n = 32,483 | n = 663 | n = 1,393 | n = 764 | n = 434 | n = 219 | |||
Age | <0.001 | |||||||
<1 year | 5,025 | 4,891 (15.06) | 25 (3.77) | 54 (3.88) | 31 (4.06) | 19 (4.38) | 5 (2.28) | |
1–5 years | 14,785 | 12,978 (39.95) | 293 (44.19) | 672 (48.24) | 466 (60.99) | 244 (56.22) | 132 (60.27) | |
5–12 years | 13,472 | 12,066 (37.15) | 312 (47.06) | 611 (43.86) | 247 (32.33) | 158 (36.41) | 78 (35.62) | |
12–18 years | 2,674 | 2,548 (7.84) | 33 (4.98) | 56 (4.02) | 20 (2.62) | 13 (3.0) | 4 (1.83) | |
Sex | 0.510 | |||||||
Female | 14,111 | 12,717 (39.15) | 248 (37.41) | 561 (40.27) | 314 (41.1) | 182 (41.94) | 89 (40.64) | |
Male | 21,845 | 19,766 (60.85) | 415 (62.59) | 832 (59.73) | 450 (58.9) | 252 (58.06) | 130 (59.36) | |
Infection Status | <0.001 | |||||||
No-infection | 8,269 | 8,269 (25.46) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Past-infection | 6,722 | 6,722 (20.69) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Primary Infection | 969 | 350 (1.08) | 113 (17.04) | 200 (14.36) | 125 (16.36) | 125 (28.8) | 56 (25.57) | |
Unknown | 2,547 | 16,568 (51.01) | 215 (32.43) | 382 (27.42) | 167 (21.86) | 79 (18.2) | 38 (17.35) | |
Activation-IgG+ | 17,449 | 574 (1.77) | 335 (50.53) | 811 (58.22) | 472 (61.78) | 230 (53.0) | 125 (57.08) | |
Diseases | ||||||||
IM | 1,510 | 347 (1.07) | 170 (25.64) | 391 (28.07) | 224 (29.32) | 236 (54.38) | 142 (64.84) | <0.001 |
Sepsis | 1,890 | 1,633 (5.03) | 26 (3.92) | 78 (5.6) | 75 (9.82) | 42 (9.68) | 36 (16.44) | <0.001 |
HLH | 405 | 193 (0.59) | 15 (2.26) | 47 (3.37) | 66 (8.64) | 53 (12.21) | 31 (14.16) | <0.001 |
Pneumonia | 14,264 | 12,942 (39.84) | 249 (37.56) | 524 (37.62) | 325 (42.54) | 149 (34.33) | 75 (34.25) | 0.012 |
CAEBV | 17 | 0 (0.0) | 2 (0.3) | 1 (0.07) | 4 (0.52) | 5 (1.15) | 5 (2.28) | <0.001 |
Lymphoma | 261 | 240 (0.74) | 4 (0.6) | 8 (0.57) | 6 (0.79) | 2 (0.46) | 1 (0.46) | 0.931 |
Immunodeficiency | 64 | 61 (0.19) | 0 (0.0) | 2 (0.14) | 0 (0.0) | 0 (0.0) | 1 (0.46) | 0.474 |
Others diagnosis | 19,583 | 18,393 (56.62) | 280 (42.23) | 552 (39.63) | 245 (32.07) | 90 (20.74) | 23 (10.5) | <0.001 |
Department at admission | 0.094 | |||||||
General ward | 33,988 | 30,709 (94.54) | 635 (95.78) | 1,325 (95.12) | 710 (92.93) | 407 (93.78) | 202 (92.24) | |
PICU | 1,968 | 1,774 (5.46) | 28 (4.22) | 68 (4.88) | 54 (7.07) | 27 (6.22) | 17 (7.76) | |
Outcome | <0.001 | |||||||
Survival | 35,662 | 32,227 (99.21) | 661 (99.7) | 1,385 (99.43) | 758 (99.21) | 420 (96.77) | 211 (96.35) | |
Death | 294 | 256 (0.79) | 2 (0.3) | 8 (0.57) | 6 (0.79) | 14 (3.23) | 8 (3.65) | |