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Table 1 Demographic, clinical and laboratory features of laboratory-confirmed chikungunya patients

From: Long-term persistence of serum IgM antibodies against chikungunya virus in patients with chronic arthralgia

Characteristics

Days post symptoms onset (DPSO) at the time of the visit

 

0–7

(N = 45)

10–30 (N = 40)

31–60 (N = 13)

61–90

(N = 7)

91–120

(N = 2)

121–720

(N = 8)

721–900 (N = 17)

901–1080 (N = 8)

1,081–1,260 (N = 3)

 > 1,260

(N = 2)

Demographics and clinical

% (n) or median (interquartile range)

Sex (female)

33 (73)

30 (75)

11 (84)

4 (57)

1 (50)

7 (87)

12 (70)

6 (75)

2 (66)

1 (50)

Age

44 (35–56)

45 (35–56)

37 (30–49)

56 (47–52)

38 (33–44)

54 (40–68)

44 (33–52)

40 (33–48)

37 (21–55)

44 (33–56)

DPSO

1

(1.5–3)

15

(13–20)

36

(37–44)

74

(67–78)

102

(96 −107)

166

(147–271)

848

(806–860)

1008

(959–1,022)

1,120

(1,120–1172,5)

1,301.5 (1,294–1308,8)

Arthralgia

45 (100)

35 (94) a

12 (92)

7 (100)

2 (100)

7 (87)

17 (100)

8 (100)

3 (100)

2 (100)

Myalgia

45 (100)

0 (0) b

8 (80) d

6 (85)

0 (0)

4 (50)

13 (76)

5 (62)

2 (66)

1 (50)

Joint edema

31 (68)

27 (75) c

12 (100) e

7 (100)

2 (100)

5 (62)

12 (75)

7 (87)

2 (66)

2 (100)

Laboratory

RT-qPCR CHIKV positive

43 (95)

5 (2)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

    Cycle Threshold

22.82

(20.0–28.4)

36.75

(35.6–37.9)

ELISA IgM positive f,h

6 (13)

40 (100)

13 (100)

7 (100)

2 (100)

5 (62)

6 (35)

1 (12)

1 (33)

1 (50)

ELISA IgG positive g,h

1 (2)

40 (100)

13 (100)

7 (100)

2 (100)

8 (100)

17 (100)

8 (100)

3 (100)

2 (100)

  1. a Data available for 35 patients
  2. b Data available for 2 patients
  3. c Data available for 27 patients
  4. d Data available for 8 patients
  5. e Data available for 12 patients
  6. f Results based on the sample-to-calibrator optical density ratio for the IgM ELISA are interpreted as follows: Negative < 0.9; Positive > 1.1; Indeterminate ≥ 0.9 and ≤ 1.1
  7. g Results based on sample-to-calibrator optical density ratio for the IgG ELISA are interpreted as follows: Negative < 0.8; Positive ≥ 1.1; Indeterminate ≥ 0.8 and < 1.1
  8. h The Sample/Calibrator ratio is calculated by dividing the optical density obtained with the test sample by the calibrator value, which is unique for the IgG ELISA and an average of a duplicate calibrator for the IgM ELISA