Fig. 4

Mechanism of action of drug candidates 2, 3, and 5c in HSV-2 inhibition. The histograms show the different percentages of HSV-2 inhibition resulting from three different mechanisms of the viral infection life cycle: adsorption, replication, and virucidal. The histogram data are expressed as the mean ± S.D. of three independent experiments of viral inhibition mechanisms of action against cell control. Groups were statistically analyzed by f tests (ANOVAs) followed by post hoc Duncan tests. Groups with different letters are considered statistically significant at p < 0.05