Table 2 Hub genes GO analysis: Based on GO database
From: Identification and validation of autophagy-related genes in sepsis based on bioinformatics studies
ONTOLOGY | ID | Description | p.adjust |
|---|---|---|---|
BP | GO:0016236 | macroautophagy | 7.15E-23 |
BP | GO:0000422 | autophagy of mitochondrion | 5.23E-22 |
BP | GO:0061726 | mitochondrion disassembly | 5.23E-22 |
BP | GO:1903008 | organelle disassembly | 2.20E-20 |
BP | GO:0000423 | mitophagy | 4.25E-12 |
CC | GO:0000407 | phagophore assembly site | 5.15E-09 |
CC | GO:0005776 | autophagosome | 5.56E-09 |
CC | GO:0005741 | mitochondrial outer membrane | 1.76E-07 |
CC | GO:0031968 | organelle outer membrane | 3.20E-07 |
CC | GO:0019867 | outer membrane | 3.35E-07 |
MF | GO:0031625 | ubiquitin protein ligase binding | 1.17E-06 |
MF | GO:0044389 | ubiquitin-like protein ligase binding | 1.59E-06 |
MF | GO:0008320 | protein transmembrane transporter activity | 9.67E-05 |
MF | GO:0022884 | macromolecule transmembrane transporter activity | 0.000137917 |
MF | GO:0140318 | protein transporter activity | 0.000186349 |