Fig. 5
From: Identification and validation of autophagy-related genes in sepsis based on bioinformatics studies
Functional enrichment analysis. A GO and KEGG functional enrichment analysis: horizontal coordinates are different GO entries enriched with the differentially expressed mitochondrial autophagy-associated genes; vertical coordinates are -log10(P value). Red color indicates biological processes, green indicates cellular components, dark blue indicates molecular functions, and light blue indicates enriched biological pathways. B Circle diagram of GO enrichment pathways, divided in an inner and outer part. Each bar in the inner circle corresponds to an entry and the height is the relative size of the adjusted p value, the higher it is the smaller the adjusted p value for that ID. C Mitophagy—animal pathway, D Ferroptosis pathway, and E NOD-like receptor signaling pathway. Each node indicates a key gene in the pathway. The color of the node is determined by log2FC, with green indicating differentially down-regulated genes and red indicating differentially up-regulated genes. GO, gene ontology; KEGG, Kyoto encyclopedia of genes and genomes; BP, biological process; CC, cellular component; MF, molecular function