Table 2 Anti-coronavirus activities of MPA and MMF
Virus | Cell | TC50 (μM) | IC50 (μM) | SI | |||
|---|---|---|---|---|---|---|---|
MPA | MMF | MPA | MMF | MPA | MMF | ||
HCoV-229E | Huh7 | > 100 ± 0 | > 100 ± 0 | 0.284 ± 0.22 | 0.165 ± 0.04 | > 352.1 | > 606.1 |
Huh7.5 | > 100 ± 0 | > 100 ± 0 | 0.352 ± 0.07 | 0.131 ± 0.08 | > 284.1 | > 763.4 | |
RPMI-2650 | > 100 ± 0 | > 100 ± 0 | 0.162 ± 0.10 | 0.153 ± 0.06 | > 617.3 | > 653.6 | |
HCoV-OC43 | C3A | > 100 ± 0 | > 100 ± 0 | 0.269 ± 0.22 | 0.638 ± 0.23 | > 371.7 | > 156.7 |
H460 | > 100 ± 0 | > 100 ± 0 | 0.107 ± 0.07 | 0.232 ± 0.02 | > 934.6 | > 431.0 | |
RPMI-2650 | > 100 ± 0 | > 100 ± 0 | 0.104 ± 0.12 | 0.086 ± 0.10 | > 961.5 | > 1162.8 | |