Fig. 4
Identification of binding epitopes of NIEAs. (a) The infection-enhancing activity of NIEAs to a series of SARS-CoV-2 single-point mutated pseudoviruses. Experiments were performed twice and data were shown in mean values. (b) These infection-enhancing results were shown by different mutations and compared with that against WT. The positive rate, geometric mean EC50, fold change, and significance of difference were labeled on the top. ‘‘-’’ represented decreased the infection-enhancing activity. The statistical significance was performed using two-tailed paired Wilcoxon test. **p < 0.01; *p < 0.05