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Table 4 Comparison of 24w and 48w HBsAg response rates in two groups of patients with different HBeAg expression

From: Impact of hepatic steatosis on the efficacy of antiviral treatment for chronic hepatitis B and the establishment of predictive model: a cohort study

Time (w)

HBeAg Neagtive (n,%)

HBeAg Postive (n,%)

24w

CHB + MASLD (n = 67)

CHB (n = 81)

P value

CHB + MASLD (n = 20)

CHB (n = 52)

P value

 

8(11.9%)

5(6.2%)

0.217

3(15.0%)

4(7.7%)

0.349

48w

CHB + MASLD (n = 66)

CHB (n = 79)

P value

CHB + MASLD (n = 16)

CHB (n = 52)

P value

 

16(24.2%)

6(12.2%)

0.005*

4(25.0%)

5(9.6%)

0.112

  1. HBsAg response was defined as a ≥ 0.5log decrease in HBsAg from baseline and pgRNA response as a ≥ 0.5log decrease in pgRNA from baseline. * indicates p < 0.05
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Virology Journal

ISSN: 1743-422X