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Table 3 Comparison of HBsAg and pgRNA response rates between CHB + MASLD and CHB group

From: Impact of hepatic steatosis on the efficacy of antiviral treatment for chronic hepatitis B and the establishment of predictive model: a cohort study

Time (w)

Parameters

HBsAg Response (n, %)

pgRNA Response (n, %)

24w

CHB + MASLD (n = 87)

10/87(11.5%)

17/55(30.9%)

CHB (n = 133)

5/133(3.8%)

12/61(19.7%)

P value

0.026*

0.163

48w

CHB + MASLD (n = 82)

20/82(24.4%)

20/41(48.8%)

CHB (n = 131)

11/131(8.4%)

13/46(28.3%)

P value

0.001*

0.049*

  1. HBsAg response was defined as a ≥ 0.5log decrease in HBsAg from baseline and pgRNA response as a ≥ 0.5log decrease in pgRNA from baseline. * indicates p < 0.05
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Virology Journal

ISSN: 1743-422X