Fig. 6
From: IL-37 attenuated HPV induced inflammation of oral epithelial cells via inhibiting PI3K/AKT/mTOR
mTOR inhibitor, Rapamycin compromises effects of IL37 on HPV induced inflammation on oral epithelial cells. A rapamycin could inhibit phosphorylated mTOR on HOEC cells; B Rapamycin could inhibit phosphorylated mTOR on IMP-H026 cells; C rapamycin compromised effects of IL37 on increase of IL18 induced by HPV on HOEC cell line; D rapamycin compromised effects of IL37 on increase of TNFɑ induced by HPV on HOEC cell line; E rapamycin compromised effects of IL37 on increase of IL18 induced by HPV on IMP-H026 cell line; F rapamycin compromised effects of IL37 on increase of TNFɑ induced by HPV on IMP-H026 cell line