Table 1 Demographic information of populations included in this meta-analysis

1

Alves [17]

Brazil

45.03 ± 13.91

145

45

37

–

153

PCR

G

2

Catalan-Soares [15]

Brazil

48.9 ± 12.74

54

84

9

–

–

SSP PCR

A, B, C

3

Deschamps [18]

Martinique

60 ± 1.43

162

85

123

–

–

SSO PCR

A, B, DRB1, DQB1

4

Elovaara [19]

USA (Japanese, Jamaican, etc.)

44.22 ± 10.81

7

5

4

–

–

N/A

A, B, C, DRB1, DQB1

5

Furukawa [20]

Japan

N/A

N/A

200

192

55

–

PCR

A

6

Goedert [21]

Jamaica

N/A

N/A

380

118

112

–

SSO PCR

A, B, DRB1, DQB1

7

Haddad [23]

Brazil

44.69 ± 14.02

155

56

49

33

150

PCR

G

8

Jeffery [24]

Japan

50.64

255

201

232

–

–

SSP PCR

A, DRB1

9

Jeffery [25]

Japan

50.64

255

201

232

–

–

SSP PCR

A, B C

10

Kozako [26]

Japan

60.57

22

35

–

32

–

SSO PCR

A

11

Lou [27]

Russia (Nivkhi)

38.66

29

4

–

–

53

PCR

A, B, C, DRB1, DQB1

12

Manns [28]

Jamaica

45

161

43

54

49

51

SSO PCR

DRB1, DQB1

13

Nishimura [29]

Japan

N/A

N/A

50

51

47

112

PCR

DRB1

14

Penova [30]

Japan

N/A

N/A

899

753

–

–

NGS

A, B, C, DQB1, DRB1

15

Rafatpanah [31]

Iran (Mashhad)

N/A

N/A

34

36

–

72

SSP PCR

A, B, C, DRB1

16

Schor [32]

Brazil

61

222

165

210

–

–

SSP and SSO PCR

A, B, C, DRB1

17

Shohat [33]

Israel (Mashhad-Japanese)

N/A

24

7

12

1

28

SSP PCR

A, B, DRB1, DQB1

18

Tafreshian [34]

Iran (Mashhad)

N/A

N/A

20

16

–

30

SSP PCR

HLA-DQB1

19

Taghaddosi [35]

Iran (Mashhad)

N/A

N/A

30

20

–

–

SSP PCR

A, B, C

20

Talledo [36]

Peru

47.44

102

94

71

–

–

PCR

A, C

21

Tarokhian [37]

Iran (Mashhad)

42.67 ± 1.94

N/A

38

33

–

–

SSP PCR

A, C

22

Treviño [38]

Spain

N/A

N/A

28

12

–

–

NGS

A, B, C, DRB1, DQB1

23

Study group [22]

Japan

56.9

115

–

–

64

340

N/A

A, B, C

24

Vine [39]

Japan

N/A

N/A

202

229

–

–

SSP PCR

A, B, C, DRB1

25

Yashiki [40]

Japan

N/A

N/A

152

148

124

175

SSP and SSO PCR

A, B, C