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Fig. 4 | Virology Journal

Fig. 4

From: Adenoviral fiber-knob based vaccination elicits efficient neutralizing antibodies and T cell responses against adenovirus infection

Fig. 4

Evaluation of immune responses to Ad5-FK in BALB/c mice. Animals were injected with Ad5-FK alone or in combination with c-di-AMP adjuvant intramuscularly three times. Two weeks after the final injection, immune responses to the Ad5-FK were assessed. (A) Serum IgG titer by ELISA (B) Infection-neutralizing antibody titer against reAd5-GFP determined in mouse sera. (C) FK-specific CD4+ and CD8 T cell responses determined by ICS and FACS. *, P < 0.05; **, P < 0.01; ***, P < 0.001

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Virology Journal

ISSN: 1743-422X