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Table 3 Comparative analysis of quality control and observed mutations in the same individual after using both nucleic acid sources (RDT strip and VTM)

From: Use of strips of rapid diagnostic tests as a source of ribonucleic acid for genomic surveillance of viruses: an example of SARS-CoV-2

Sample

38111*

38126

38133

38157

38160

38162

RDT strip

RDT strip

VTM

RDT strip

VTM

RDT strip

VTM

RDT strip

VTM

RDT strip

VTM

Coverage (%)

95

96

95

99

99

99

99.7

94

82

92

99.7

QC overall score

17

26

11

0

0

0

0

91

268

55

0

Total missing

1437

124

1217

126

240

253

1903

1903

4719

231

62

Deletion

18

24

6

27

30

24

18

43

9

9

6

Substitution

69

71

66

78

78

76

76

66

62

62

80

Reverse private mutation

0

1

0

0

0

0

0

0

0

0

0

Labeled private mutation

1

2

1

1

1

0

0

0

0

0

0

Unlabeled private mutation

2

3

1

2

2

1

2

4

5

5

5

Variant

BA.5.2.1

BA.5.2

BA.5.2.1

BQ.1.1

BQ.1.1

BQ.1.1

BQ.1.1

BQ.1.1

BQ.1.1

BQ.1.1

BQ.1.1

  1. 38111* only RDT samples were sequenced
  2. GISAID:
  3. EPI_ISL_15581444
  4. EPI_ISL_15581445
  5. EPI_ISL_15581450
  6. EPI_ISL_15581457
  7. EPI_ISL_15581458