Virology Journal

Table 2 IgG antibody titres against SARS-CoV-2 in responders after infection and vaccination

From: Humoral immunity to SARS-CoV-2 in kidney transplant recipients and dialysis patients: IgA and IgG patterns unraveled after SARS-CoV-2 infection and vaccination

	Infected		Vaccinated
	N	Median [IQR]	n	Median [IQR]	p-value
IgG antibodies against RBD
Overall	65	18.23 [9.38; 20.05]	260	19.33 [16.05; 20.90]	0.02
KTR	19	18.28 [12.97; 20.13]	72	10.85 [3.07; 18.72]	0.02
HD	23	16.82 [8.14; 20.46]	76	17.07 [15.68; 19.23]	0.77
Control	23	16.29 [9.30; 19.62]	115	19.93 [19.54; 22.44]	< 0.001
IgG antibodies against S1S2
Overall	65	16.96 [10.32; 22.29]	248	16.64 [8.40; 21.34]	0.27
KTR	19	15.49 [9.33; 21.92]	60	5.85 [1.89; 12.27]	< 0.001
HD	23	19.01 [12.97; 23.35]	76	14.97 [6.75; 19.88]	0.009
Control	23	15.13 [7.11; 20.50]	112	20.57 [16.07; 22.16]	0.004
IgG antibodies against NP
Overall	66	35.10 [12.97; 38.27]		NA
KTR	20	20.70 [8.30; 36.78]		NA
HD	23	35.81 [33.15; 39.11]		NA
Control	23	34.51 [15.10; 37.87]		NA

Table showing the titres (median values, signal/noise ratio) of IgG antibodies directed to RBD, S1S2 and NP of SARS-CoV-2 in responders. Time from PCR or first vaccine to blood sample was not correlated with the IgG RBD titres (n = 248, r_s = 0.04, p = 0.50) while it was weakly correlated with the IgG S1S2 titres (n = 236, r_s = 0.17, p = 0.01). KTR Kidney transplant recipients, HD hemodialysis

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ISSN: 1743-422X

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