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Table 1 Proportion of patients developing IgG antibodies and neutralizing capacity against SARS-CoV-2 after infection and vaccination

From: Humoral immunity to SARS-CoV-2 in kidney transplant recipients and dialysis patients: IgA and IgG patterns unraveled after SARS-CoV-2 infection and vaccination

Infected

Vaccinated

 
 

N

N (%)

N

N (%)

p-value

IgG antibodies against RBD

 Overall

69

65 (94.2)

326

260 (79.7)

0.004

 KTR

22

19 (86.4)

129

72 (55.8)

0.007

 HD

24

23 (95.8)

85

76 (89.4)

0.45

 Control

23

23 (100.0)

112

112 (100.0)

*

IgG antibodies against S1S2

 Overall

69

65 (94.2)

326

248 (76.1)

0.001

 KTR

22

19 (86.4)

129

60 (46.5)

0.001

 HD

24

23 (95.8)

85

76 (89.4)

0.45

 Control

23

23 (100.0)

112

112 (100.0)

-

IgG antibodies against NP

 Overall

69

66 (95.7)

 

NA

 

 KTR

22

20 (90.9)

 

NA

 

 HD

24

23 (95.8)

 

NA

 

 Control

23

23 (100.0)

 

NA

 

Neutralizing capacity

 Overall

69

62 (89.9)

152

145 (95.4)

0.14

 KTR

22

20 (90.9)

21

17 (80.9)

0.41

 HD

24

23 (95.8)

24

21 (87.5)

0.61

 Control

23

19 (82.6)

107

107 (100.0)

0.001

  1. Table showing the proportion of patients who developed IgG antibodies against RBD, the S1S2 domain of SARS-CoV-2, NP and neutralizing capacity. Numbers highlighted in bold indicate statistical significance. KTR Kidney transplant recipients; HD hemodialysis; RBD receptor binding domain, NP nucleocapsid protein. *no variation