Table 1 Characteristics of demography, clinical data, cytokines and lymphocyte subsets of the patients with SFTS

Age (years), mean ± SD

65.05 ± 7.92

62.92 ± 7.63

68.77 ± 7.08

< 0.001

Gender

Male (%)

46 (47.9%)

28 (45.9%)

22 (62.9%)

0.109

Female (%)

50 (52.1%)

33 (54.1%)

13 (37.1%)

Diabetes (%)

13 (13.5%)

6 (9.8%)

7 (20.0%)

0.161

Hypertension (%)

23 (24.0%)

13 (21.3%)

10 (28.6%)

0.422

Coronary disease (%)

6 (6.3%)

4 (6.6%)

2 (5.7%)

0.870

Immunological parameters

 IL-6 (pg/ml), median (IQR)

9.59 (3.28–33.68)

5.40 (2.50-13.94)

30.00 (10.16–71.81)

< 0.001

 IL-8 (pg/ml), median (IQR)

4.85 (1.16–19.14)

3.20 (1.03–9.56)

15.44 (3.28–40.10)

0.002

 IL-10 (pg/ml), median (IQR)

5.19 (2.03–17.86)

2.83 (1.27–9.93)

14.50 (5.64–44.25)

< 0.001

 IFN-α (pg/ml), median (IQR)

4.27 (0.63–67.31)

2.50 (0.27–24.73)

24.81 (2.50-175.40)

0.006

 IFN-γ (pg/ml), median (IQR)

13.54 (2.50-97.24)

14.99 (2.50-89.74)

12.09 (1.69-211.47)

0.867

 CD4⁺ cell counts/µl, median (IQR)

250 (120–467)

338 (148–552)

160 (75–251)

< 0.001

 CD8⁺ cell counts/µl, median (IQR)

253 (118–460)

300 (140–546)

160 (91–305)

0.016