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Fig. 5 | Virology Journal

Fig. 5

From: Differences in neutralizing antibody sensitivities and envelope characteristics indicate distinct antigenic properties of Nigerian HIV-1 subtype G and CRF02_AG

Fig. 5

Cross-clade reactivity of subtype G and CRF02_AG PSV and HIV+ plasma. Plasma pool neutralization was evaluated in the TZMbl neutralization assay against the subtype G and CRF02_AG PSV and reference strains for subtype A, B, C, D and CRF02_AG. Sensitivity to neutralization by plasma pools from pure HIV-1 subtypes/CRFs was determined for all A) subtype G and C) CRF02_AG PSV. Plasma potency was determined against PSVs from different HIV subtypes/CRFs for the B) subtype G and D) CRF02_AG plasma pools. Statistical differences were determined using Mann Whitney U Test; * = p<0.05, ** = p<0.005, *** = p<0.0005

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