Table 2 Mixed infection with other causative agents based on tNGS
|  | All patients (No. = 96) | Mild pneumonia (No. = 71) | Severe pneumonia (No. = 25) | P value |
|---|---|---|---|---|
With mixed infection, No., (%) | 91 (94.8) | 66 (93) | 25 (100.0) | 0.173 |
With mixed virus infection, No., (%) | 43 (44.8) | 25 (35.2) | 18 (72) | 0.001 |
 EBV, No., (%) | 15 (15.6) | 12 (16.9) | 3 (12) | 0.752 |
 HRV-A, No., (%) | 12 (12.5) | 7 (9.9) | 5 (20) | 0.168 |
 CMV, No., (%) | 8 (8.3) | 5 (7.0) | 3 (12) | 0.425 |
 HRSV, No., (%) | 6 (6.3) | 1 (1.4) | 5 (20) | 0.004 |
 HPIV type3, No., (%) | 6 (6.3) | 4 (5.6) | 2 (8) | 0.649 |
 HCoV, No., (%) | 6 (6.3) | 5 (7.0) | 1 (4) | 1.000 |
 Other viruses, No., (%) | 12 (12.5) | 7 (9.9) | 5 (20) | 0.289 |
With mixed bacterium infection, No., (%) | 74 (77.1) | 55 (77.5) | 19 (76) | 0.881 |
 SPN, No., (%) | 40 (41.7) | 32 (45.1) | 8 (32) | 0.346 |
 Hin, No., (%) | 50 (52.1) | 36 (50.7) | 14 (56) | 0.816 |
 KP, No., (%) | 8 (8.3) | 6 (8.5) | 2 (8) | 1.000 |
 MC, No., (%) | 9 (9.4) | 7 (9.9) | 2 (8) | 1.000 |
 SA, No., (%) | 7 (7.3)a | 4 (5.6) | 3 (12) | 0.372 |
 Other bacteria, No., (%) | 8 (8.3) | 8 (11.3) | 0 (0.0) | 0.107 |
With mixed fungus infection, No., (%) | 16 (16.7) | 10 (14.1) | 6 (24) | 0.348 |
 C. albicans, No., (%) | 12 (12.5) | 8 (11.3) | 4 (16) | 0.504 |
 Other fungus, No., (%) | 4 (4.2) | 3 (4.2) | 1 (4) | 1.000 |