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Table 1 Main mutations in the RBD of Variants of concern and subvariants of the Omicron and their stability values generated from the DUET webserver

From: Computational analysis of affinity dynamics between the variants of SARS-CoV-2 spike protein (RBD) and human ACE-2 receptor

  1. Red color destabilizing mutations, Green color stabilizing mutations. All the stability values are presented in kcal/mol
  2. Abbreviations: D Decreased stability, De Destabilizing, In Increased stability, O Omicron, RBD Receptor-binding domain, S Stabilizing, VOCs Variants of concern